Dr. rer. nat. Arzu Çelik, Associate Professor


Mailing Address:
Bogaziçi University
Department of Molecular Biology and Genetics
North Campus, Kuzey Park, KP 302
34342 Bebek - Istanbul
Turkey

Tel.: +90 (212) 359 7562
Fax: +90 (212) 287 2468
email: arzu.celik@boun.edu.tr









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Education


1996 - 2002 Doctor of Philosophy in Genetics
under supervision of Prof. Dr. S.I. Korsching
University of Cologne, Institute for Genetics, Cologne, Germany
Restricted and Complementary Expression Patterns of Eph Receptors and Ephrin Ligands Define Potential Interaction Sites in the Embryonic and Adult Olfactory System of Zebrafish, Danio Rerio.

1994 - 1995 Master of Science in Molecular Biology and Genetics
Under supervision of Prof. Dr. B. Kırdar
Boğaziçi University, Department of Molecular Biology and Genetics
Studies on the Molecular Analysis of Turkish BMD/DMD Patients.

1989 - 1994 Bachelor of Science in Biology
Rank: 3rd best GPA




PROFESSIONAL ACTIVITIES

2014 Visiting Scientist in Dr. Christian Klambt's Lab
University of Münster, Institute of Neuro-and Behavioral Biology, Münster, Germany

since 2012 Associate Professor Boğaziçi University, Department of Molecular Biology and Genetics, Istanbul, Turkey

since 2007 Assistant Professor Boğaziçi University, Department of Molecular Biology and Genetics, Istanbul, Turkey

2002 - 2007 Post-Doctoral Research in Prof. Claude Desplan's Lab
New York University, Center for Developmental Genetics, New York, USA
Establishment of a novel piggybac enhancer-trap screen for photoreceptor differentiation
Control of stochastic choice between two cell fates: role of spineless
Role of iroquois-complex genes in receptor exclusion.

2002 Visiting Scientist in Dr. Michael Coleman's Lab
University of Cologne, Zentrum für Molekulare Medizin, Cologne, Germany



PAPER/GRANT REVIEW

  • Member Grant Review Committee: French National Research Agency (ANR), France
  • ad hoc grant reviewer for: The Netherlands Organisation for Scientific Research (NWO)
  • ad hoc grant reviewer for: The Research Foundation Flanders (FWO)
  • ad hoc reviewer for Nature Methods
  • ad hoc reviewer for PLOS Genetics
  • ad hoc reviewer for Development Genes and Evolution
  • ad hoc reviewer for Functional & Integrative Genomics
  • ad hoc reviewer for BioResearch
  • ad hoc reviewer for JoVE
  • ad hoc reviewer for Turkish Journal of Biology
  • ad hoc reviewer for Turkish Journal of Zoology


AWARDS


1996 - 2000 Ph.D. fellowship from the German Academic Exchange Service (DAAD)
2008 EMBO Young Investigator Award (Installation Grantee)
2008 Turkish Academy of Sciences, Young Investigator Award


MEMBERSHIPS


since 2002 Genetics Society of America (GSA)
since 2004 Turkish-American Scientists and Scholars Association (TASSA)
since 2011 Junior European Drosophila Investigators (JEDI) http://www.fly-jedi.org/
since 2011 Founding Member of Molecular Biology Organization (Turkey) http://www.molbioturk.org/mbd/
since 2013 Turkish Neurology Society
since 2014 Brain Research Society


GRANTS

EMBO Installation Grant, 2008-2013
TÜBITAK Career Development Grant 107T775, 2008-2010
FP7-MBG BRIDGE, 2009-2014
TÜBİTAK Grants, 1001, 111T446, 112T275, 113T086, 215Z369


RESEARCH PAPERS

  • Çevrim BÇ, Mika K, Callaerts P, and Çelik A (2017) The cell adhesion molecule Unzipped mediates neuron-neuron and neuron-glia interactions to control mushroom body development. submitted to Scientific Reports
  • Köstler S, Alaybeyoğlu B, Weichenberger CX, and Çelik A (2015) FlyOde – a platform for community curation and interactive visualization of dynamic gene regulatory networks in Drosophila eye development. F1000Research 4:1484-9.
  • Potier D, Davie K, Hulselmans G, Sanchez MN, Haagen L, Huynh-Thu VA, Koldere D, Çelik A, Geurts P, Christiaens V, and Aerts S (2014) Mapping gene regulatory networks in Drosophila eye development by large-scale transcriptome perturbations and motif inference. Cell Reports 9:1-14.
  • Tsachaki M, Mishra AK, Rister J, Ng J, Çelik A, and Sprecher SG (2013) Interplay of Sens and Php13 controls photoreceptor development, differentiation and transformation in Drosophila. PLoS Genetics 9(12):e1004027.
  • Li X, Erclik T, Chen Z, Venkatesh S, Morante J, Çelik A, and Desplan C (2013) Temporal specification of neuroblasts controls neuronal diversity in the Drosophila medulla. Nature 498(7455):456-62.
  • Vasiliauskas D, Mazzoni EO, Sprecher SG, Johnston RJ Jr, Lidder P, Vogt N, Çelik A, and Desplan C (2011) Feedback from Rhodopsin controls Rhodopsin exclusion in Drosophila R8 photoreceptors. Nature 479(7371):108-12.
  • Mazzoni EO, Çelik A, Wernet MF, Vasiliauskas D, Cook TA, Johnston RJ, Pichaud F, and Desplan C (2008) Iroquois-Complex genes induce co-expression of visual pigments in Drosophila. PLoS Biology 6(4):e9.
    Full Text (HTML) | PDF
  • Wernet MF, Çelik A, Mikeladze-Dvali T, and Desplan C (2007) Generation of uniform fly retinas. Current Biology 17(23):r1002-3.
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  • Wernet MF*, Mazzoni EO*, Çelik A*, Duncan DM, Duncan I, and Desplan C (2006) Stochastic spineless expression creates the retinal mosaic for colour vision. Nature 440(7081):174-180. *equal contribution
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  • Laser H, Conforti L, Morreale G, Mack TG, Heyer M, Haley JE, Wishart TM, Beirowski B, Walker SA, Haase G, Çelik A, Adalbert R, Wagner D, Grumme D, Ribchester RR, Plomann M, and Coleman MP (2006) The slow Wallerian degeneration protein, WldS, binds directly to VCP/p97 and partially redistributes it within the nucleus. Molecular Biology of the Cell 17(3):1075-84. Epub 2005 Dec 21.
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  • Adalbert R, Gillingwater TH, Haley JE, Bridge K, Beirowski B, Berek L, Wagner D, Grumme D, Thomson D, Çelik A, Addicks K, Ribchester RR, and Coleman MP (2005) A rat model of slow Wallerian degeneration (WldS) with improved preservation of neuromuscular synapses. European Journal of Neuroscience 21(1):271-7.
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  • Çelik A*, Fuss SH*, and Korsching SI (2002) Selective targeting of zebrafish olfactory receptor neurons by the endogenous OMP promoter. European Journal of Neuroscience 15(5):798-806. *equal contribution
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  • Çelik A, Eraslan S, Gökgöz N, Ilgın H, Başaran S, Bökesoy I, Kayserili H, Yüksel-Apak M, and Kırdar B (1997) Identification of the parental origin of polysomy in two 49,XXXXY cases. Clinical Genetics 51(6):426-9.
    Abstract
  • Schlüter G, Çelik A, Obata R, Schlicker M, Hofferbert S, Schlung A, Adham IM, and Engel W (1996) Sequence analysis of the conserved protamine gene cluster shows that it contains a fourth expressed gene. Molecular Reproduction and Development 43(1):1-6.


REVIEWS

  • Şahin HB, and Çelik A (2013) Drosophila eye development and photoreceptor specification eLS. John Wiley & Sons, Ltd: Chichester. DOI:10.1002/9780470015902.a0001147.pub2.
  • Morante J, Desplan C, and Çelik A (2007) Generating patterned arrays of photoreceptors. Current Opinion in Developmental Genetics 17(4):314-9. Review
    Full Text (HTML) | PDF
  • Fuss S, Çelik A, and Desplan C (2007) Olfactory identity kicked up a Notch. Nature Neuroscience 10(2):138-140. News&Views
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  • Mazzoni EO, Desplan C, and Çelik A (2004) 'One receptor' rules in sensory neurons. Developmental Neuroscience 26(5-6):388-95. Review
    Full Text (HTML) | PDF


EDITED BOOKS

  • Decoding Neural Circuit Structure and Function
    Editors: A Çelik and MF Wernet, Springer, 2017


PERSONAL THESES


A. Çelik (2001) Restricted and Complementary Expression Patterns of Eph Receptors and Ephrin Ligands Define Potential Interaction Sites in the Embryonic and Adult Olfactory System of Zebrafish, Danio Rerio.
Ph.D. thesis Institute of Genetics, University of Cologne, Cologne, Germany
PDF

A. Çelik (1995) Studies on the Molecular Analysis of Turkish BMD/DMD Patients.
Master's Thesis Department of Molecular Biology and Genetics, Boğaziçi University, Istanbul, Turkey

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